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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
8.48
Human Site:
S344
Identified Species:
14.36
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S344
G
P
E
V
P
P
A
S
S
A
M
T
H
L
S
Chimpanzee
Pan troglodytes
XP_509441
819
90122
R304
Q
G
C
E
H
T
S
R
T
E
D
P
F
I
Q
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
S344
G
S
E
V
P
P
A
S
S
G
V
T
H
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
A344
A
P
E
M
P
S
P
A
S
S
S
S
S
S
G
Rat
Rattus norvegicus
Q6AXT8
471
49872
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
S344
S
D
A
P
L
P
P
S
P
L
L
Q
V
S
G
Frog
Xenopus laevis
NP_001084764
548
60887
S83
T
Y
S
F
G
K
T
S
S
C
H
L
S
I
D
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
S337
T
Q
A
S
L
L
S
S
L
P
L
S
T
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Q339
Q
Q
E
P
P
Q
M
Q
Q
S
L
P
V
G
M
Honey Bee
Apis mellifera
XP_394429
1014
115124
Q462
P
P
Y
A
M
E
I
Q
T
V
L
T
P
V
Q
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
S347
Q
M
R
R
S
A
S
S
S
A
S
L
H
Q
M
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
N460
L
A
S
Q
G
Q
Q
N
I
F
S
A
Q
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
A558
P
P
P
L
P
A
A
A
S
K
P
S
E
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
0
0
80
N.A.
26.6
0
N.A.
N.A.
13.3
13.3
6.6
N.A.
13.3
13.3
26.6
0
P-Site Similarity:
100
20
0
86.6
N.A.
53.3
0
N.A.
N.A.
20
20
26.6
N.A.
26.6
33.3
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
0
15
22
15
0
15
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
29
8
0
8
0
0
0
8
0
0
8
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
15
8
0
0
15
0
0
0
0
8
0
0
0
8
15
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
22
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
0
15
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
8
15
8
0
0
8
8
29
15
0
15
15
% L
% Met:
0
8
0
8
8
0
8
0
0
0
8
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
15
29
8
15
36
22
15
0
8
8
8
15
8
8
8
% P
% Gln:
22
15
0
8
0
15
8
15
8
0
0
8
8
15
15
% Q
% Arg:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
15
8
8
8
22
43
43
15
22
22
15
15
15
% S
% Thr:
15
0
0
0
0
8
8
0
15
0
0
22
8
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
8
8
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _